Abstract
Atmospheric pressure spray (APS) mass spectra of thermolabile and nonvolatile compounds such as saccharides, glycosides, peptides, phospholipids and glycolipids are presented. The APS method can produce intense protonated and/or cationized molecules such as (M+H)+, (M+Na)+ and (M+K)+ for these compounds without any buffers or external ion sources, unlike other ionization methods. The APS method combined with a collision-induced dissociation technique can provide significant fragment ions, which are very useful for structural elucidation.
