2012 Volume 53 Issue 11 Pages 1956-1961
Surface hydrophilicity is considered to have a strong influence on the biological reactions of bone substituting materials. However, the relationship between hydrophilicity and osteoconductivity has not been discussed quantitatively. In this study, Ti substrates were coated with TiO2 having different water contact angles, using anodizing in aqueous solutions containing different types of solute ion, and the quantitative relationship between hydrophilicity and osteoconductivity was investigated.
All of the anodized coatings were anatase-type TiO2 with a fine surface roughness. Most of the solute ions were included in the coatings, but they did not influence the hydrophilicity of the anodized coatings. However, the surface hydrophilicity of the anodized coatings depended on the pH of the aqueous solution. The amount of hard tissue formed on TiO2-coated specimens (denoted as RB-I) depended on the water contact angle on their surface. For water contact angle between 20 (deg.) and 55 (deg.), the value of RB-I increased as water contact angle decreased. On the other hand, for water contact angle between 55 (deg.) and 70 (deg.), the value of RB-I increased as water contact angle increased.