MEMBRANE
Online ISSN : 1884-6440
Print ISSN : 0385-1036
ISSN-L : 0385-1036
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Antithrombogenic Technology of Polysulfone Dialyzer
Yoshiyuki Ueno Hiroyuki Sugaya
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2015 Volume 40 Issue 3 Pages 161-164

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Abstract
The patients in an advanced renal failure are generally treated with a dialyzer as a substitute for their kidney. The antithrombogenicity is highly required to the hollow fiber membrane inside a dialyzer. We developed “Toraylight” NV which was improved antithrombogenicity. There are three viewpoints, that is, optimizing the header shape of the dialyzer, improvement of the quality of the hollow fiber membrane form and the antithrombogenicity of hollow fiber membranes.
Applying the antithrombogenic polymer (NV polymer) to the PSf membrane surface in the nanometer order, we created an extremely antithrombogenic hollow fiber membrane for hemodialysis, which made the number of the platelet adhesion less than a hundredth compared with a conventional PSf membrane with PVP polymer.
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