抄録
A strategy focused on water structures near polymer surfaces to develop low–fouling membranes is demonstrated. Based on surveys on the relationships between the antithrombogenic properties of biomaterials and the hydration states of the biomaterial polymers, we supposed that the membranes whose pore surfaces are modified with such polymers having the unique water structures in their hydrated states would have low–fouling properties. In this review, some typical characteristics in water structures of zwitterionic polymers and poly(2–methoxyethylacrylate), both of which are known as excellent biomaterials, are summarized. Then the excellent low–fouling properties of the microfiltration membranes and ultrafiltration membranes modified with carboxybetaine–based polymers and poly(2–methoxyethylacrylate) are demonstrated. These membranes hardly fouled and maintained the initial fluxes when the aqueous solutions containing 1000 ppm BSA were filtered below 6 × 10–6 m3 m–2 s–1 of filtration fluxes.
