抄録
Biological cell membranes are composed of lipid bilayers and various functional lipophilic macromolecules including membrane proteins and have excellent functions such as molecular recognition and selective permeation against target molecules. To artificially reproduce the structure of biological cell membranes, reconstitution techniques of self–standing lipid bilayer structures, such as liposomes and black lipid membranes, have been established. However, the physical instability due to their self–standing structure restricts practical applications. On the other hand, supported lipid bilayers (SLBs) are lipid bilayers immobilized on a flat solid surface and have been attempted to various applications such as sensor and separation due to their high stability. In this report, our recent studies to expand SLBs to various polymeric substrates were introduced. SLBs were formed on porous flat substrates and spherical substrates, and applied to water purification membranes and giant liposomes, respectively.
