抄録
Lipid nanoparticles, which have been actively studied in recent years under the influence of the COVID–19 vaccine, are diverse in their structure and properties. Due to the complexity of their structure, their physicochemical properties are still difficult to elucidate. One possible solution is to extend the analytical methods that have been used for lipid membrane systems. We have developed a method for fluorescence analysis of lipid membranes with the aim of applying it to a wider range of targets, including a variety of lipid nanoparticles. Here, the methodology is presented along with examples of the evaluation of lipid nanoparticles using multiple analytical tools based on our knowledge of membrane analysis.
