抄録
Drug delivery (DD) from aqueous medium into biomembranes is crucial as a primary step of the bioactivity. The application of the highly developed NMR method to both sides of drugs and membranes is expected to make a significant contribution to advances in the DD study. We have unambiguously specified the bilayer interface and interior as DD sites on the atomic level, taking advantage of the site-selective, noninvasive NMR. The method can be widely applied to a variety of drugs such as anesthetics and endocrine disruptors (EDs).
