Abstract
The graft survival after renal transplantation has been improved especially after the development of new immunosuppressive drugs. Before that, in the better matching of HLA we selected the donor, the better survival of the graft we could get after renal transplantation. Now, many people think the role of histocompatibility matching became less important. But it’s not true. In cadaveric donor renal transplantation, no mismatch of the HLA leads excellent survival of the graft. Before and after organ transplantation, using high sensitive anti-HLA antibody testing developed recently, we can predict and prevent the antibody mediated rejections. To understand the importance of histocompatibility testing in organ transplantation, the present status of renal transplantation is reported. Moreover, the problems of the histocompatibility testing in present organ transplantation and the outlook of histocompatibility testing for the future are described.
