Development of Eyelash Growth Technology with The Latest Human Stem Cell Culture Supernatant —Collaboration with M Regenerative Clinic—

Abstract

Recently, masks have become a must-have item due to the COVID-19 problem. The eye area not covered by mask, especially the eyelashes, has become an important part of a person’s first impression. In recent years, human stem cell culture supernatant has been attracting attention as a new cosmetic ingredient born from regenerative medicine technology for the purpose of growing eyelashes thicker and longer. The various growth factors and cytokines contained in the supernatant powerfully activate cells involved in hair growth, producing a strong hair-growing effect. However, due to the large molecular size of the supernatant contents, it has been difficult to penetrate the supernatant contents to the cells deep inside the pores, the target site for eyelash hair growth. In this paper, we focus on this human stem cell culture supernatant and report on its eyelash growth effect by combining it with PLGA nanoparticles’ DDS (Drug Delivery System) technology we have built which can deliver supernatant contents to the target site well.