Development and Practical Use of Integrating Regenerative Medicine and Nanotechnology

Abstract

Human Stem Cell Culture Supernatant, a product of regenerative medicine and stem cell research, contains various cell growth factors and bioactive substances. It has diverse and multifaceted mechanisms of action, so that it is capable of activating cellular functions and promoting the production of constituent components. Consequently, it has attracted attention as a groundbreaking cosmetic ingredient and is being used accordingly.

In this paper, the functionality of a smart technology that fuses human stem cell culture fluid and PLGA nanospheres was verified. The results suggest excellent collagen-producing ability, especially in the epidermis and dermis, and indicate that the technology can be expected to be utilized in aging care cosmetics. It has been demonstrated that PLGA NS work as a highly useful delivery technology, which facilitates penetration of ingredients like HSCCS, despite their large molecular size, deep into the skin, and retains them at the site of action, ensuring a long-lasting effect.