2001 Volume 50 Issue 1 Pages 11-15
The effects of excess intake of a fermented milk, specially prepared with Lactobacillus plantarum ONC141, on blood biochemical parameters and condition of defecation were studied in 11 healthy adults (average age 30±9 years). The subjects consumed 600 ml/day for six weeks. Ten healthy adults consumed the same amount of regular whole milk as the control group. Serum total cholesterol levels in the fermented milk group increased significantly in the 4th week of ingestion, however this was only temporary. The milk group showed a similar change. There were no other paticular changes in any of the other blood biochemical parameters in either group. Diarrhea was observed in the fermented milk group as 1.9% of the total defecation by frequency, but at a lower percentage than in the milk group (6.3%). No change was seen in either group in defecation frequency, fecal quantity and fecal hardness. There was a tendency of improvement in feeling of defecation in the fermented milk group. No paticular subjective symptoms were observed during fermented milk ingestion. These results suggest that excess intake of the specially prepared fermented milk may not cause any problematic adverse reactions in healthy people.
