Abstract
The general toxicity and the immunosuppressive effect of Phellinus lintenus were examined in rats and mice. From acute oral administration tests at doses up to 2,000 mg/kg, no toxic or lethal effects were observed resulting from the mycelial components. Furthermore, orally administered mycelial components exerted type-I allergy suppressive effects by inhibiting production of serum IgE and inhibiting formation of dermatitis-like skin lesions. These effects were more evident from hot-water extracts, as compared with culture filtrates.
