Abstract
Degradation of dibenzo p-dioxin (DD) by an edible ectomycorrhizal mushroom, Lyophyllum shimeji, was examined. DD was degraded by treatment with L. shimeji, resulting in the metabolite monohydroxylated DD. DD degradation was significantly inhibited by the addition of cytochrome P450 monooxygenase inhibitors and inhibited by the generation of hydroxylated DD. These results suggest that L. shimeji can metabolize DD to a monohydroxylated compound, most likely mediated initially by the cytochrome P450 system. This is the first report of an ectomycorrhizal fungus with the ability to metabolize DD.
