赤血球の大いさに関する研究

赤血球平均面積と有核赤血球平均面積の相関について

抄録

The author has studied the correlativity of the size of the erythrocytes and the nucleated red cells, by measuring the mean area both the erythrocytes and the nucleated red cells of the patients with several kinds of anemia by means of planimetry.
The results were summarized as follows:
1) Mean value of the erythrocyte area of twenty healthy adults was (45.36±1.16)μ².
2) The size of the erythrocytes was correlated to that of considerably matured erythroblasts on seven healthy adults, five cases with hypochromic anemia and a case with the same disease who had been received the iron therapy, and seven cases with schistsomiasis japonica.
3) On four cases of panmyelopathia with gradual course, the size of the erythrocytes was correlated to the size of the comparatively matured erythroblasts. No correl-ation was recognized between the size of the erythrocytes and the erythroblasts on four cases who were suffering from chronic leukemia, but the coefficient of correlation was relatively large.
4) The studies, carried out on a patient with pernicious anemia during the treatment with vitamin B₁₂, revealed that the size of the erythrocytes was correlated. well to that of the nucleated red cells, especially to the size of the considerably matured ones.
5) The size of the erythrocytes was interrelated well to that of the nucleated red cells, to deliberate on all subjects en bloc.
6) No correlation was noticed between the size of the erythrocytes and the erythroblasts of the three cases of acute leukemias and two panmyelopathias with rapid course, but on such cases most of the circulating erythrocytes have no direct connection with the erythroblasts in the bone marrow in all probability.
From these observations, the author gained an impression that, in general, the size of the erythrocytes is mutually related with the size of the considerably matured nucleated red cells.