The net production of serum albumin and γ-globulin by human liver slices in vitro was studied by means of immunochemical quantitative precipitation reaction.
The results were as follows:
1. The average values of net production of albumin and γ-globulin in 5 cases of nonliver diseases was 0.17 and 0.07mg. per g. of the liver per hour, respectively.
2. The correlation between the net production of albumin and that of γ-globulin was found.
3. In cases of liver diseases the net production of albumin decreased correlating with their liver function (Bromsulphalein test, Takata test.). However, the net production of γ-globulin did not decrease in liver diseases except for icteric cases, but rather increased in some cases.
