尿インドール誘導体諸反應の意義に就いて

抄録

The studies were performed from various angles to clarify the reasons why the results obtained from Parri's, Davis' as well as Obermayer's reactions that were equally considered to be the methods to find indole derivatives in urine do not always coincide with each other.
The results obtained from this study are summerized as follows:
Chromogen in Parri's reaction consists mainly of indican.
As a method to find indican, Obermayer's reaction is more sensitive than Parri's reaction. It is negative in Davis' reaction by using indican alone, but it turns to be positive in case added to isatin or negative urine of Davis' reaction.
The above mentioned three reactions will never be affected by indole, scatole, 1-tryptophan, isatin or indolacetic acid.
Observing a normal rabbit made after the injection of indole, Parri's, Davis' and Obermayer's reactions proved to be all positive. But in case the scatole injection was made, only Parri's reaction became positive. The three reaction were all negative when indolacetic acid, 1-tryptophan or isatin had been injected.
When the injection of indole was made to a liver injured rabbit, longer time was required to start showing the positive Porri's reaction than that to a normal rabbit, while Davis' reaction was negative, and excretions of chromogen in Parri's reaction and indican were reduced.
In case indole was injected to a rabbit that was burdened with the extract of cancer urine, Parri's and Davis' reactions kept positive longer compared with the rabbit that injected of uric extract of the healthy man.