抄録
In this study, we demonstrated a simple preparation of size-controlled fullerene C60 micro-/nano- particles. The fullerene particles were prepared through the reaction of fullerene C60 with a diaminoalkane. The resultant particles were spherical and their size depended on the alkyl chain length of the diaminoalkane compounds. In addition, we successfully modified the hydrophilic surface of the fullerene nanoparticles using succinic anhydrite. The obtained hydrophilic particles are dispersible in water, and the resultant solution is injectable into animals. This surface modification, which involves the introduction of -COOH groups onto the particle surface, may allow the nanoparticle to be tethered to functional moieties such as fluorescence dyes, oligosaccharides, antibodies and drugs. Thus, these simple preparations can widely extend the application of these particles in various fields particularly in biology.
