抄録
Background Up till now, there has been no detailed study on an association between impaired fasting glucose (IFG) and metabolic risk factors by age and gender in Japanese.
Methods Stepwise logistic regressions using IFG as a dependent variable and BMI, metabolic risk factors, age, drinking status, and smoking status as independent variables were performed by age and gender in non-diabetic Japanese without antihypertensive and/or antihyperlipidemic medication, or any history of cardiovascular disease.
Results Correlations between fasting plasma glucose and obesity indices were stronger in women ≤50 years than in men ≤50 years, but were weaker in women >50 years than in men >50 years. Age, BMI, HDL cholesterol, gamma glutamyltransferase (GGT), and LDL cholesterol in men ≤50 years, BMI, TG, ALT, and drinking status in men >50 years, heart rate and BMI in women ≤50 years, and uric acid and drinking status in women >50 years were independently associated with IFG.
Conclusion Uric acid was the only metabolic risk factor to be independently associated with IFG in apparently healthy non-diabetic Japanese women >50 years. (Ningen Dock 2010; 24: 43-47)
