Abstract
An autopsied case of severe burn was reported. A 24-year old man had a burn of grade 2-4 involving 70% of the body surface and was immediately admitted to the hospital. Fluid transfusions were started and it improved shock states of the patient. On the first hospital day Ht was 57%, urine output was 240ml/day. After then he continued the good hospital course until the six hospital day, which time suddenly his temperature rose to 39.6°C and he developed dyspnoea and tachycardia, terminally urea nitrogen was 50mg% and blood pressure 78% mmHg. Blood transfusion, diuretics was given, however he expired on the same day. At autopsy there were severe pulmonary hemorrhage and edema. The both kidneys appeared pale and swollen. There were multiple petechial hemorrhages on the surface. Histologically the proxymal tubules revealed massive vacuole degeneration. There was no evidence of hemorrhagic casts. The adrenals showed the atrophic adrenal cortex, and in the fascicular layer there were numerous vacuoles in the cortical cells. There were multiple mucosal erosions in the esophagus and colon. The immediate cause of death was attributed to the severe pulmonary hemorrhages and edema.
