抄録
1) After being taken orally, a causal agent (hapten) is combined with the mucous membrane to form anti-hapten-mucosa antibody.
2) This antibody has chemotaxis to the orifice regions through its carrier specificity.
3) When a sensitized subject takes a causal drug orally, a new fixed drug eruption would develop on a region inflamed and congested for some time by insect bite, fungal or bacterial infection etc., because the concentration of antigen and antibody rises there.
4) The keratinocytes and dermal macrophages take the antigen-antibody complexes and give the antigenic information to the lymphocytes through the macrophages of a regional lymphnode, where the epidermis affinity antibody is much more produced.
