Abstract
Birbeck granule (Bg)-like structure (BgS) was observed in interdigitating reticulum cell-like cells which increased in lymph nodes of the DNCB-sensitive mice, the following was evident.
1. BgS was composed of two layers of limiting membrane and one layer of internal lamina, as in the case of Bg rods. The BgS were thinner than the Bg, and the internal lamina of BgS had no periodicity as observed in Bg.
2. BgS was often associated with discoid body and rough-surfaced endoplasmic reticulum (r-ER)-like structure showing “reticular pattern”.
3. BgS was continuous with the r-ER.
Thus BgS obviously differs from Bg in structure. A remarkable difference between the two is the finding which BgS may be derived of r-ER.
