The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
Clinical Case Reports
A Case of Toxic Shock-like Syndrome with Soft Tissue Necrosis on Face
Narihiro AKIMOTOMikio KAWAIMasaharu MIZUNO
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2012 Volume 74 Issue 2 Pages 174-177

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Abstract
We report a 37-year old male presented erythematous swelling on his forehead with fever of 40 degrees. The patient had suffered no previous illness. Laboratory investigations showed consumptive coagulopathy with clinical manifestations of shock and development of renal failure. A rapid detection kit for the group A streptococcal antigen showed positive results from exudate in the necrotic area of the right eyelid, and we diagnosed him as toxic shock-like syndrome (TSLS). We administered penicillin and clindamycin and started plasma exchange and continuous hemodifiltration with intensive supporting care, leading to a successful outcome. TSLS is a life-threatening infection, but early diagnosis and appropriate therapy may reverse this threat. A rapid detection kit for the group A streptococcal antigen might be useful test for early diagnosing TSLS.
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© 2012 by Western Japan Division of JDA
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