抄録
The patient was a 61-year-old woman. She consulted a first hospital because of knee pain. She was introduced to our institution for close examination due to insufficient fracture of the tibia, atrophic change in her whole bone, and higher serum alkaline phosphatase. She showed low BMD (0.662g/cm², 55% of YAM), high biochemical markers, high excretion of urine calcium and slight increase of serum high sensitive PTH. Suspecting dysfunction of the parathyroid, more examinations were performed. Detecting goiter by the neck US and increase in serum thyroid hormone, hyperthyroidism was diagnosed. We treated her by medication first, which improved the better thyroid function and recovered more bone mass.