Twelve cases of pyogenic osteomyelitis were treated with antibiotic impregnated bone paste between September 2003 and October 2004. The average age was 57.2 years (19 to 78 years) at the time of surgery. The mean follow-up period was 8.1 months (two to 12 months). Among these cases, seven had diabetes mellitus, one had erythroderma exfoliativa, and the remaining four had no history. The cultured bacteria were methicillin resistant staphylococcus aureus (MRSA) in seven cases, mixed organism in two cases, and pseudomonas aeruginosa, methicillin sensitive staphylococcus aureus (MSSA) in one case respectively. All cases were cured with no evidence of the reccurence. We concluded that antibiotic impregnated bone paste provides satisfactory results in treatment of pyogenic osteomyelitis.
