足関節に発生せるいわゆる色素性絨毛結節性滑膜炎の1例

抄録

Pigmented villonodular synovitis, tenosynovitis, and bursitis are well known and not unknown. The etiology of this disease is unknown.
Jaffe, Lichtenstein (1941) concluded that the lesion is an inflammatory response to some unknown agent and that the disease is not a true tumor or neoplasm.
Prior to this time, this disease was known by varions names, including xanthoma, xanthogranuloma, giant-cell tumor, myeloplaxoma and benign polymorphocellular tumor of the synovial membrane etc.
Microscoically, this desease is characterized by hyperplasia and proliferation of synovial-lining cells and undifferentiated connective-tissue cells of the synovial membrane with formation of large number of polyhedral or spindleshaped stromal calls.
These cells may contain abundant lipid, hemosiderin, or both and multinuclear giant cells are common.
A case of pigmented villonodular synovitis in the left ankle was reported in this paper.
A nineteen year-old female was first seen on December 1968, with a complaint of pain and swelling in the left ankle. There was no history of injury. Two months before admission, the pain, which was present with use, but not at rest. There was a good, painless range of motion. Roentgenograms revealed no pathological findings. A diagnosis of bursitis in the left ankle was made.
At operation on December 28, 1968, an irregular, nodular, yellowish, brown, soft tumor was encountered which extended from ankle joint into the Chopart-joint.
A synovectomy, as comlete as possible, was performed, The microscopic diagnosis was pigented villonodular Synovitis.