わが国における軟部悪性腫瘍の概況

抄録

Malignant soft tissue tumors in Japan were reviewed in collaboration with the specialists of orthopedics and pathology. The files of 695 patients with soft tissue sarcoma were registered and classified as: liposarcoma 155 cases (22.3%), rhabdomyosarcoma 118 (17.0%), neurogenic sarcoma 55 (7.9%), fibrosarcoma 52 (7.5%), leiomyosarcoma 51 (7.3%), angiosarcoma 48 (6.9%), synovial sarcoma 31 (4.5%), dermatofibrosarcoma protuberans 26 (3.7%), alveolar soft part sarcoma 12 (1.7%) and malignant fibrous histiocytoma 9 (1.3%). Suspected cases were 70 (10.1%), and unclassified were 54 (7.8%).
Angiosarcoma, dermatofibrosarcoma protuberans and malignant fibrous histiocytoma tend to occur more frequently in males, neurogenic sarcoma in females. The highest average age was 48.8 years of liposarcomas, the lowest 21.7 years of rhabdomyosarcomas, 65% of which occured under 10 years of age. The lower extremity was most often involved in liposarcoma, leiomyosarcoma and synovial sarcoma.
Wide resection or amputation with chemotherapy and irradiation were common in the management of the tumor. But, 5-years survival rates were as follows: liposarcoma 64%, fibrosarcoma 59%, leiomyosarcoma 50%, neurogenic sarcoma 44%, synovial sarcoma 30% and angiosarcoma 32%. The survival of rhabdomyosarcoma was only 21%.