整形外科と災害外科
Online ISSN : 1349-4333
Print ISSN : 0037-1033
ISSN-L : 0037-1033
抗痙攣剤の長期服用に続発したクル病の1例
大屋 國益黒瀬 真之輔池本 和人近藤 正一佐伯 満坂田 洋三大津 和生江口 正雄
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1978 年 27 巻 1 号 p. 113-117

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A boy, 10 years old, who came to the division of orthopedic surgery for his fracture of right clavicle, showed remarkable appearances of biochemical and radiologic abnormalities of rickets.
He suffered from epilepsy following influenza vaccination at seven months after birth and has received anticonvulsant medication over nine years.
At about four months since he has been treated with Ethosuximide and Diazepam instead of the administrations of Diphenylhydantoin, Trimethadion, Primidone, Phenobarbital, Mephobarbital and Acetazolamide, enlargements of the antebrachial bone ends disappeared; fraying and cupping of the metaphyses and the wide growth discus on X-ray were almost improved; and elevation of the serum alkaline phosphatase activity (29 B. U.) decreased to 11 B. U..
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