A patient, 39-year-old male, first had noticed a small subcutaneous tumor in his calf in 1970. This tumor had been resected twice on May and June in 1976. But the tumor showed a local recurrence and metastases to the regional lymphnodes, which were also removed after the administration of ADR.
A distant soft part metastasis, noticed on his back on February in 1977, became small by the effect of chemotherapy with ADR.
Histologically, the tumor cells with blunt-ended nuclei in the interlacing cords were high gradely anaplastic. The mitotic rate was elevated (1-5/HPF).
Reticulin was usually present and a majority of the fibrosis was parallel with the long axis of the tumor cells.