1980 年 29 巻 3 号 p. 453-455
The case described in this report was born with premature labor of 31 weeks and 2 days, and died 20 minites later. Autopsy showed a 26.2cm long, 1680gr premature boy with short arms and legs, and prominent abdomen.
X-ray examination showed severely retarded ossification of vertebral bodies; absent ossification of the sacrum, barrelshaped thorax with short ribs of no fractures, very short tubular bones with metaphyseal flare and cupping, and small iliac bones with crescent-shaped inner and inferior margins.
Microscopic examination showed disorganized pattern of cartilage, and swelling of cells and reduced matrix of resting layer.