先天性内反足の筋生検 -特に組織化学的染色の所見について-

抄録

Histochemical staining methods were applied to the study of congenital clubfoot. Muscles were obtained from 51 patients, mostly under the age of five years.
Altogether 62 biopsies were examined. The site of muscle biopsies were gastrocnemius (38) and abductor hallucis (24).
Histochemical anomalies were revealed in 42 specimens (68%); fiber type grouping (4), fiber type predominance (17), type I fiber hypotrophy (25) and type II fiber hypotrophy (6).
These anomalies considered to be neurologically determined, so the evidence sugested the neurogenic factor as the causation of congenital clubfoot.