A case of “Membranous Lipodystrophy” with serious bone lesions was presented.
The patient, a 39-year-old man, visited our clinic complaining of marked swelling and/or deformities of almost all joints in the extremities. He had the past history of numerous pathological fractures and the family history of consanguineous marriage. Roentgenograms showed expansion of the bone marrow spaces in the epiphyseometaphyseal areas. The C. T. scan. was found useful for diagnosis of the lesion. The E. E. G. and the C. T. scan. of the skull revealed an organic change in the brain. On histological examination, so-called membranocystic lesion was also observed in the subcutaneous tissue.
