老人性骨粗鬆症における補体系ならびに Proteinase Inhibitor の血中動態について

抄録

For the purpose of elucidating the cause of senile osteoporosis and developing its therapy, complement system and proteinase inhibitors (α₂M, α₁AT, α₁X) were evaluated as clinical parameters. They were measured as factors related to pathophysiology and the clinical profile. The following results were obtained. C3 in senile osteoporosis was high in 37%. C4 showed various levels from low to high. α₂M was within normal level, α₁AT was generally increased. α₁X was either normal or high.