軟部悪性腫瘍を中心とした治療成績の検討

抄録

Thirty-five cases of malignant soft part tumors which were treated at our clinic from 1971 to 1984, and were 24 males and 15 females, were reviewed clinically and histopathologically. They were composed of 8 liposarcomas, 6 leiomyosarcomas, 6 neurogenic sarcomas, 3 rhabdomyosarcomas, 2 malignant fibrous histiocytomas, 2 alveolar soft part sarcomas, one synovial sarcoma, one extra abdominal desmoid, one hemangiopericytoma and 5 undifferentiated sarcomas.
The survival rate (of each malignant soft part tumor) was influenced by each histopathological type, that is, liposarcoma, malignant fibrous histiocytoma, synovial sarcoma, extra abdominal desmoid and hemangiopericytoma showed the higher survival rate (5/8, 2/2, 1/1, 1/1, 1/1, respectively), whereas leiomyosarcoma and undifferentiated sarcoma had the lower survival rate (1/6, 1/5 respectively).
The radical operations, including wide local resection, amputation and disarticulation, resulted in the higher survival rate. On the other hand, the extirpation resulted in the lower survival rate.
Concerning with time of operations, the less than twice radical operation led to the higher survival rate, the more than third led to the lower survival rate.
Grading the tumors by GTNM (UICC calssification), stages I and II showed the better survival rate, but stages III and IV showed the poor survival rate.
These facts indicated that the radical operation should be primarily done for malignant soft part tumors.