Spinal epidural abscess is an uncommon disease and difficult in the early diagnosis. Delay of the diagnosis often leads to increase of the morbidity and mortality. In this paper we reported four cases of epidural abscess following epidural or satellite ganglion block. Decompressive laminectomy was carried out in all the cases. Two of them recovered from complete paralysis but the other two failed in the recovery of myelopathy and died from renal and respiratory failures. One of these was subjected to autopsy and the findings were described.