Eight patients with bone sarcoma and fifteen patients with soft part sarcoma were treated with combination chemotherapy (VACA therapy) consisting of Vincristin, Actinomycin D, Cyclophosphamide and Adriamycin.
Cumulative five years survival rate by Kaplan-Meyer method was about 62% in soft part sarcoma. In bone tumors, only 2 cases have survived in the long period. VACA therapy is considered to be a useful combination chemotherapy for soft part sarcoma.
