In this paper, we reported the clinical courses and discussed the usefulness of laboratory, radiographical and histological examinations from a retrospective review of 13 patients (7 males, 6 females, mean age of 50.8 years) who had been diagnosed as having chronic non-specific arthritis of the hands clinically and histologically. At the time of the final follow-up study, 6 patients (46%) were diagnosed as developing rheumatoid arthritis, 1 was infectious arthritis and the remaining 6 patients were unclassified non-specific arthritis.
As a result, the patients with rheumatoid arthritis were significantly younger than those with non-specific arthritis and markedly showed bony atrophy, erosion and joint space narrowing radiographically and lining cell proliferation, villi formation, plasma cell infiltration and lymph follicles formation histologically. These findings could suggest the subsequent clinical courses of rheumatoid arthritis.