Since the opening of Oita Medical College Hospital ten years ago, in 1981, 187 patients with bone or soft tissue tumors have been seen in our Orthopedic Division. Among eleven patients with osteosarcoma, three patients were diagnosed as having a periosteal osteosarcoma, low grade central osteosarcoma and extraskeletal osteosarcoma, respectively. Eight patients with conventional osteosarcoma were treated and four were still alived with no evidence of disease recurrence.