We report two cases of suspected massive osteolysis
Case 1 was a 63-year-old man who experienced pain in his left buttock six years ago and was walking with a limp the following year. X-ray showed resorption of the left coxal bone and pubic bone. Suspecting a malignant tumor, biopsy was performed. The findings showed massive osteolysis which had destroyed bone trabeculaes, and replaced granulomatous fibrosis including blood vessels. Eracatonin may be effective for stopping the activity of the osteoclast and relieving pain.
Case 2 was a 66-year-old man who noticed a large mass on his left shoulder one year ago. The growing tumor limited his shoulder R. O. M. Radiography, especially 3DCT scan, showed marked resorption of the left scapula and ribs. Hematological and pathological findings revealed a multiple myeloma.
Massive osteolysis is a very rare tumor-like lesion characterized by progressive osteolysis. The diagnosis must be confirmed by the microscopic finding of an intramedullary angioma-like vascular structure. Therefore, it is necessary to distinguish this disease from others having osteolysis.
