Neurologia medico-chirurgica
Online ISSN : 1349-8029
Print ISSN : 0470-8105
ISSN-L : 0470-8105
Case Reports
Intracranial Germinoma With Syncytiotrophoblastic Giant Cells in the Cerebellopontine Angle
—Case Report—
Kazunori FUJIWARAHiroshi UENOHARAHiroyoshi SUZUKIYoshiharu SAKURAI
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JOURNAL OPEN ACCESS

2002 Volume 42 Issue 3 Pages 132-136

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Abstract
A 23-year-old man presented with a 3-week history of left hearing disturbance and left facial nerve paresis. T1-weighted magnetic resonance (MR) imaging showed an iso-intense mass in the left cerebellopontine angle (CPA), with homogeneous enhancement with gadolinium-diethylenetriaminepenta-acetic acid. T2-weighted MR imaging showed the mass as heterogeneously iso- to hyperintense. Gross total removal of the tumor was achieved. Histological examination revealed that the tumor was a germinoma with syncytiotrophoblastic giant cells. Whole central nervous system irradiation with cisplatin-etoposide chemotherapy was performed postoperatively. He has been in good condition with no sign of recurrence for 7 years. Intracranial germ cell tumors in the CPA are very rare. Total surgical removal followed by irradiation and chemotherapy will provide a good outcome.
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© 2002 by The Japan Neurosurgical Society

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