Abstract
In Cerebrovascular “Moyamoya” Disease, children and adults show different aspects of abnormal net-like vessels (called “Moyamoya”) at the base of the brain. The reason for the difference has not been clarified as yet. In order to explain the reason, this study was undertaken to investigate possibilities and morphology of the anastomosis among the perforating branches as well as the influence of their aging by means of micro-angiography and/or graphical reconstruction of serial sections.
1) Three groups of fetuses, children and adults were subjected to the study of the aging of Aa. corporis striati mediae. The number, courses, and shapes of vessels, that is, such items as diverting angle at the middle cerebral artery, smoothness or irregular changing of their courses or directions as well as diameters are carefully observed by microangiography. Changes with aging were found remarkable among all of these items. It must be noted that the younger had the more arteries, suggesting easiness of collateral formation.
2) The existence of anastomosis among the perforating branches with one another, between these vessels and Aa. medullaris were clearly verified by graphical reconstruction of serial sections. It was also observed that the pattern of the anastomosis and the caliber of each anastomosis varied with aging. This observation may well indicate that the “Moyamoya” vessels appeares as collateral pathways based on the perforating branches and also that “Moyamoya” vessels are easily formed in the younger than in the older.
