Abstract
Brain infarction confined to the anterior half of the thalamus can be produced in dogs by simultaneously occluding 4 main arteries ipsilaterally at the base of the brain (the internal carotid, the anterior cerebral, the middle cerebral, and the posterior communicating arteries). Using this “thalamic infarction model in the dog”, hemorrhagic infarction following recirculation was investigated.
In animals undergoing 6-12 hour occlusion, a high incidence of hemorrhagic infarction was found following recirculation. Notably, in brains autopsied 1 hour after recirculation, hemorrhagic infarction was seen in all (100%) of the dogs.
