Abstract
In experimental cerebral infarction models of dogs, 10-15 ml of 20% Fluosol DA was used to estimate its effectiveness on the basis of improvement in microcirculation and changes in the size of infarction lesions. Comparative studies were also performed on four other groups consisting of the control (nonmedicated group), mannitol group (2 g/kg), low-molecular dextran group (10 ml/kg) and mannitol +Fluosol DA group.
Fluosol DA was effective even when used alone, but its combination with mannitol proved the most effective. It was concluded that Fluosol DA should be an effective medicine for acute cerebral infarction.
