Abstract
Long-term cultures of murine glioma-specific killer T cell clone (G-CTLL) were established. G-CTLL cells were maintained in T cell growth factor (TCGF)-dependent exponential proliferative culture for more than 7 months, over which time the cells continued to mediate antigen-specific cytotoxic activity. The cytotoxic activity of the G-CTLL cells was blocked by adding only anti Lyt-2, but not Lyt-1, monoclonal antibody.
