Primary Cerebral Ganglioneuroblastoma
Case Report
1983 Volume 23 Issue 4 Pages 301-304
Details
1983 Volume 23 Issue 4 Pages 301-304
A case of primary cerebral ganglioneuroblastoma was reported.
One month prior to admission, the patient, a 36-year-old female, suffered from generalized convulsions. Neurological examination showed no pathological findings, but CT scan revealed a calcification surrounded by an enhanced area in the left frontal lobe. A left frontotemporal craniotomy was performed and the brain tumor was totally removed. The tumor was greyish white, soft, poorly vascularized and cleary margined. Postoperative neurological deficit was mild expressive aphasia. Since Linac therapy with whole brain dosage of 1, 090 rads induced leukopenia, further irradiation and chemotherapy was discontinued and only OK-432 was given. More than three years after the operation CT scans have not revealed any sign of recurrence. Histologically, the tumor was composed of two cell types, small and large. The small cells or neuroblasts were poorly differentiated and had positive silver impregnation of fibers. The large cells or ganglion cells had round vesicular nuclei, deeply staining nucleoli, and Nissl granules in their cytoplasm.
