Abstract
An infant case of huge epithelium-lined cyst in the posterior fossa is reported. The cyst was located in the prepontine region of the posterior fossa with extension to the bilateral middle cranial fossae, through the tentorial incisura. It had no communication with the ventricular system or subarachnoid space. The cyst wall was lined with ciliated columnar and cuboidal epithelial cells which were completely invested by a basement membrane. The diagnosis and the management of such cases were discussed and the pathogenesis of the cyst was reviewed.