Abstract
A case of metastatic intracranial germ cell tumor from the testis is reported. A 27-year-old man underwent orchidectomy in January, 1982, and received systemic chemotherapy from January to September, 1982. In October, 1982, the patient was readmitted because of an episode of generalized seizure. Enhanced computerized tomography (CT) revealed round high density areas in the left frontal and right occipital lobes, which suggested metastatic intracranial tumors. Whole brain irradiation therapy was started. Upon completion of 8 Grey (Gy) irradiation, the patient developed right hemiparesis and motor aphasia. CT revealed an increased irregular high density area which was indicative of bleeding from the left frontal lesion. In October, craniotomy and removal of the hematoma and the tumor were performed. Two days later the patient complained of a headache. CT showed another bleeding from the right occipital lesion. Evacuation of the hematoma and removal of the tumor were again performed. In November, CT disclosed additional new bleeding in the left occipital lesion and the patient eventually died in November, because of respiratory failure.
The surgical indication, follow-up of human chorionic gonadotropin and alpha fetoprotein, immunohistochemical results of metastatic intracranial germ cell tumors from testis are discussed with a review of the literature.
