Neurologia medico-chirurgica
Online ISSN : 1349-8029
Print ISSN : 0470-8105
ISSN-L : 0470-8105
In Vitro Effects of ACNU, BCNU, CDDP, and Bleomycin on Human Glioma Cells
Kinzo IWATAW.K. Alfred YUNGWilliam S. FIELDS
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1988 Volume 28 Issue 10 Pages 965-969

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Abstract
In an in vitro study, the chemosensitivity of EFC-2 human glioma cells to ACNU, BCNU, cisplatin, and bleomycin sulfate was evaluated by growth suppression and colony forming assays. The EFC-2 cell line was cloned from a human glioblastoma multiforme. Cisplatin was the most effective agent in this study. ACNU and BCNU had very similar dose-response curves, although this result was not statistically significant.
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© The Japan Neurosurgical Society
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