Abstract
1) When the essential oil of the black-rotten sweet potato was orally given to the young rats 0.01_??_0.02g per day during twenty days, there was no remarkable effect on their growth but when the oil was given 0.02_??_0.03g per day, their growth was remarkabily retarded.
2) When the oil was orally given to the rats, once 0.1_??_0.2g per 120_??_150g body weight, all rats died within 27_??_42 hours.
3) When the oil was abdominally injected to mice, almost all of them died within 24_??_48 hours.
4) The rats which died in the experiment mentioned above were examined pathologically, and fatty degeneration of the liver, hemorrhage of the lung, and retrogressive change of the heart were obviously recognized. The small intestine, kidnies and the stomach were also injured.
5) The oil was harmless to the fowls when orally administered 0.1g per 1kg body weight, but their appetite was disturbted when given more than 0.2g per 1kg. Some parasites were put out.
6) The oil was harmless to men when taken less than 0.3g per day.
7) The urine which was excreted by adult rabbits when the essential oil was orally given was compared with the normal urine. The result was as follows: Creatinine increased about 30%; creative increased remarkably during 2_??_3 days and then decreased gradually; acetone bodies increased to about 1.5_??_3 times; glycuronic acid increased slightly; urea showed no change; protein and indican were not excreted.
