Formation of Tryptamine by Microbes

Abstract

The formation of tryptamine from tryptophan was examined employing pure and mixed culture methods with the microbial suspensions prepered from the home-made Miso containing tryptamine.
The amount of tryptamine produced by the mixed culture method was up to 36% of DL-tryptophan added to the media. However, by the pure culture method, it was produced only about 1% in amount of the added tryptphan. Tyramine present in the yeast extracts was found to be an effective tryptamine producing factors. Furthermore, the tryptamine production was acceralated by the addition of nicotinic acid and pridoxal, besides tyramine, resulting in the production of tryptamine up to 90% in amount of the added DL-tryptophan.