Effect of Fruit Extracts on the Growth of Cultured Human-derived Cells
1992 Volume 39 Issue 2 Pages 193-196
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1992 Volume 39 Issue 2 Pages 193-196
The growth-promoting activity in fruit extracts (38 kinds) was screened using cultured human-derived cells in serum-free medium. A human-human hybridoma cell line (HB 4 C 5) and a human promyelocytic leukemia cell line (HL 60) were cultured in ERDF medium and in ERDF medium supplemented with insulin, transferrin, ethanolamine and selenite. Extract of various fruits promoted the growth of HB 4 C 5 and HL 60 in serum-free medium with or without ITES. A higher growth-promoting activity on HB 4 C 5 cells was shown by the extracts of akebi, grapefruit, grape, plum (dry), mango, melon, litchi, and that on HL 60 was shown by extracts of akebi, kiwi fruit, pear, banana, grape, plum, mango and melon.
